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Robust disease model for
Relapsing-Remitting Multiple Sclerosis
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Relapsing/Remitting Multiple Sclerosis (RR-MS) is the most frequent form of Multiple Sclerosis.
Neurofit offers a disease model for MS in the rat that mimics the RR-MS in human.
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Highlights:
Clear periods of remission and relapse
Relapse phase as severe as in the first attack
Robust assay to evaluate potential drug for the treatment of MS
Provides dosing flexibility for the testing of different treatment strategies (e.g., preventive or curative treatment, treatment of relapse, etc...)
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Integration of the Area Under each Curve used as a measure of Disease load
(disease severity)
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Dexamethasone therapy initiated at the peak of the first attack (blue bar) reduces by 80% the severity of the disease relapse
Dexamethasone therapy initiated at the first sign of second attack (red bar) reduces by 50% the severity of the disease relapse |
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In addition, NEUROFIT offers a range of validated in vitro and in vivo screening tests for psychiatry, neurology and oncology.
For a complete listing, please refer to our website.
If you need further information, please do not hesitate to contact us. We look forward to hearing from you.
Kind regards,
NEUROFIT
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Tel : +33 (0)3 88 65 16 06
Fax: +33 (0)3 88 65 16 22
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