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PRECLINICAL RESEARCH
Therapeutic Areas - Models-Assays - Programs - Research Collaboration - Oncology

Catalogue 2008
Therapeutic areas :
Screening tests organised by therapeutic area.
Models and Assays :
Disease models and assays organised by in vitro or in vivo method.
Programs :
Compound Profiling:
Design of screening programs for specific target indications.
Phenomouse Program:

Phenotyping of mutant or transgenic mice by behavioural, histological and biochemical tests.
Research Collaboration :
NEUROFIT can function as a integral part of your research organisation.
Oncology :
NEUROFIT is pleased to announce the expansion of our services in Oncology :

The inhibition of blood vessel formation (neovascularization) and the disruption of blood vessels within the tumor is one of the most promising therapeutic strategies for treating cancer. Neurofit offers in-vitro as well as in-vivo preclinical assays to screen new drug candidates for Oncology.

ASSAY DESCRIPTION
Capillary Formation Assesses the ability of endothelial cells to form capillaries on Matrigel
Capillary Disruption Assesses the ability of compounds to disrupt capillaries on Matrigel
Endothelial Proliferation Measures the proliferative capacity displayed by endothelial cells
Proliferation Cancer Library Measures the proliferative capacity displayed by cancer cells
Permeability Assesses the ability of compounds to alter the permeability of a endothelial cell monolayer
Morphology Assesses changes in endothelial cell morphology
Vascular Disruption Qualitative & quantitative measure of blood vessel perfusion in tumor and normal tissues
Tumor Xenograft Qualitative & quantitative measure of tumor growth
MTD Maximum tolerated dose studies
DRF Dose range finding study